Yoshito Kishi Selected Research

Buruli Ulcer

8/2017	Mycolactone cytotoxicity in Schwann cells could explain nerve damage in Buruli ulcer.
1/2017	Design, synthesis, and cytotoxicity of stabilized mycolactone analogs.
11/2015	Simple, Rapid Mycobacterium ulcerans Disease Diagnosis from Clinical Samples by Fluorescence of Mycolactone on Thin Layer Chromatography.
1/2015	Efficacy of Rifampin Plus Clofazimine in a Murine Model of Mycobacterium ulcerans Disease.
1/2014	Accelerated detection of mycolactone production and response to antibiotic treatment in a mouse model of Mycobacterium ulcerans disease.
11/2012	Photochemistry of mycolactone A/B, the causative toxin of Buruli ulcer.
9/2012	Synthesis and structure of two new mycolactones isolated from M. ulcerans subsp. shinshuense.
8/2012	Mycobacterium ulcerans causes minimal pathogenesis and colonization in medaka (Oryzias latipes): an experimental fish model of disease transmission.

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Yoshito Kishi Research Topics

Disease

8	Buruli Ulcer 08/2017 - 08/2012
4	Neoplasms (Cancer) 05/2012 - 08/2004
1	Carcinoma (Carcinomatosis) 01/2017
1	Melanoma (Melanoma, Malignant) 01/2017
1	Tuberculosis (Tuberculoses) 01/2015
1	Hearing Loss (Hearing Impairment) 01/2015
1	Neglected Diseases 01/2014
1	Fibrosarcoma 05/2012
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 05/2012
1	Breast Neoplasms (Breast Cancer) 05/2012
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 05/2012
1	Glioblastoma (Glioblastoma Multiforme) 05/2012
1	Head and Neck Neoplasms (Head and Neck Cancer) 05/2012
1	Leiomyosarcoma 05/2012
1	Pancreatic Neoplasms (Pancreatic Cancer) 05/2012
1	Prostatic Neoplasms (Prostate Cancer) 08/2004
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 08/2004

Drug/Important Bio-Agent (IBA)

3	mycolactoneIBA 08/2017 - 08/2012
3	mycolactone AIBA 01/2017 - 09/2012
2	eribulin FDA Link 05/2012 - 01/2011
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2015
1	Rifampin (Rifampicin)FDA LinkGeneric 01/2015
1	Streptomycin (Streptomycin Sulfate)FDA Link 01/2015
1	Clofazimine (Lamprene)FDA Link 01/2015
1	AcidsIBA 01/2014
1	AnthracyclinesIBA 05/2012
1	taxaneIBA 05/2012
1	SaltsIBA 05/2012
1	ER 076349IBA 01/2011
1	methanesulfonic acid (methanesulfonate)IBA 12/2007
1	KetonesIBA 08/2004
1	halichondrin BIBA 08/2004
1	Biological ProductsIBA 08/2004
1	Aligeron (AS 2)IBA 08/2004
1	Caspase 3 (Caspase-3)IBA 08/2004

Therapy/Procedure

1	Intramuscular Injections 01/2015
1	Skin Transplantation (Skin Grafting) 01/2015
1	Therapeutics 01/2015